立志成為漫畫家的高中生林明子，經同學介紹來到一個奇怪的美術教室。這個教室沒有招牌也沒有宣傳，甚至在電話本上都查不到，只是一處坐落在海邊的小木屋。木屋主人是個手拿竹刀、身穿運動服的美術老師，名叫日高健三。他嚴厲無比，每次學生們畫畫懈怠的時候，他只有一句話：“去畫吧！”

　　在孔雀鎮的鐵路旁邊，生活著一個有著灰暗過去的男子——約翰·斯基爾帕（希里安·墨菲 Cillian Murphy 飾），他自幼在母親的淫威下長大，由此養成了壓抑自閉的性格。在母親去世后，約翰的人格分裂，其內心生出象征母性的女子埃瑪。約翰就這樣在男女兩個身份間轉換，過著平靜而扭曲的隱蔽生活。　　某個清晨，災禍突然降臨。一個火車頭脫軌闖入約翰家的院子，正在晾曬衣物的埃瑪受到驚嚇，并且出現在小鎮人民的面前。人們對此議論紛紛，約翰則希望盡快將火車頭清除院子，然而政客們卻打算以此作為政治斗爭的砝碼。面對種種混亂的局面，約翰和埃瑪的心中焦慮重重，他們的矛盾也漸次激化……

　　麥可(狄恩肯恩飾)在路上搭載了年輕性感的正妹(克莉絲汀波森飾)，麥可原先認為漫漫公路有正妹相伴艷福不淺，自以為遇上了豔遇的他，卻不知道自己即將陷入一連串的陰謀及殺機，一趟沒有終點的旅程即將展開…　　故事描述一個男人在路途中載了一位年輕的女人，原來只是好心借人搭便車，結果男主人公卻發現自己陷入了一場可怕的午夜夢魘……　　If she looks too good to be true, then she absolutely is. Just ask Michael Anderson (Dean Cain), a gullible film editor who picks up a sexy young hitchhiker (Christie Burson) in the Arizona desert. After the most thrilling one night stand of his life, Michael becomes embroiled in a twisted love con involving a sadistic crime boss (Michael Madsen), a lonely henchman, and a thieving bank manager. Trust isn't just a bitch, it's a dirty little trick!　　A crime bosss money is missing and he wants it back by any ay means. The beautiful hitchhiker has it and wants to make the getaway.　　Alexander "Sasha" Shulgin is the scientist behind more than 200 psychedelic compounds - including MDMA, more commonly known as Ecstasy. Considered to be one of the greatest chemists of the 20th century, Sasha's vast array of discoveries have had a profound impact in the field of psychedelic research, making him a subject of fascination and controversy among fellow scientists and a folk hero to recreational users of psychedelics. Dirty Pictures uncovers the lifework of Dr. Shulgin and takes  viewers inside his Northern California home where he lives with his wife of 40 years and continues to carry out experiments in a makeshift laboratory. Director étienne Sauret likewise delves into the broader world of psychedelic research - where the fields of chemistry, neuroscience and philosophy intersect - and investigates whether or not this particular field could aid in solving the deepest mysteries of the human mind.

 基克爾（弗雷德里克·馬奇 Fredric March 飾）是一名知識非常淵博的科學家，他將畢生的經歷都投注到了探索人性的善惡奧妙之中，并且最終制造出了一種可怕的藥劑，這種藥劑能夠令基克爾化身成為海德先生，基克爾將自己所有的惡意和壞念頭都投射到了海德的大腦里。白天，基克爾行醫救人樂善好施，待到夜幕降臨，海德先生便會現身，殺人害命，無惡不作。基克爾有一位名叫伊芙（米利亞姆·霍普金斯 Miriam Hopkins 飾）的未婚妻，兩人之間的感情非常的要好，然而，海德先生的存在讓基克爾不自覺的被名叫碧翠絲（Eric Wilton 飾）的放蕩妓女所吸引。分裂的人格讓基克爾感到萬分的痛苦，他想要消滅海德先生。