不知曾幾何時，地球突然爆發恐怖的喪尸病毒，成千上萬的人被病毒感染，隨后化作嗜血喪尸撕咬同類，正常人類的數字直線減少。帕特里克（馬修·福克斯 Matthew Fox 飾）和杰克（杰弗里·多諾萬 Jeffrey Donovan 飾）當年乘坐巴士疏散，誰知途中遭遇最慘烈的 事件，這兩個男人以及一個尚在襁褓中的小嬰兒成為唯一的幸存者。九年后，地球上人類所剩無幾，杰克以及當年的嬰兒——可愛的小女孩露（奎恩·麥克科甘 Quinn McColgan 飾）住在一個寒冷的山村，父女倆相親相愛，甜蜜溫馨。與之相對，胡子拉碴的帕特里克與他們比鄰而居，他似乎與杰克有著深深的隔膜。　　某個飄雪的夜晚，露意外在院落外目擊到久未出現的喪尸的行蹤，曾經的噩夢再度浮現……

　　A group of friends must confront their fears in a terrifying game.

 旅にはいつも出會いと別れがある。

　　The boisterous, arrogant professor Challenger, a reputed biologist and anthropologist, dares the London Zoological Society to mount an expedition to verify his spectacular claim, without physical proof, that his previous expedition to the Amazonian basin found live dinosaurs. Apart from him and his 'socialite' counterpart, professor Summerlee, it consists of experienced discoverer Lord Roxbury, the young reporter Ed Malone -who got publicly struck down with Challenger's umbrella at his arrival- and Jennifer Holmes, Malone's news agency's boss's daughter, essentially as conditions for putting up the money. In Brazil they are joined by Jennifer's brother David and local 'guide' Manuel Gomez. They soon discover the dinosaurs are real and dangerous, like giant spiders, but loose their helicopter and thus are desperate for a way down from the isolated plateau. They learn Roxbury knew about the fate of Burton White, an explorer whose diary they find, thus presume to be dead, in search of diamonds, and confirmation of the local tribe being the lethal guardians of the plateau's secrets, but also get surprising help...