2008年金融危機下，美國內華達州昂皮爾小鎮的重要經濟支柱石膏廠倒閉，人去鎮空，這里的郵政編碼也被取消。丈夫去世后，幾乎在在昂皮爾小鎮度過了一生的弗恩（弗蘭西斯·麥克多蒙德飾）無力獨撐生活。為了將生活成本壓到最低，她將簡陋的家當搬上了改裝后的廂式貨車，開始了一邊打工、一邊西行的公路生活。她在亞馬遜流水線上、在游樂園的咖啡廳里、在國家森林公園做臨時工。一路上，她和許多廂式貨車寄居者相遇、相識，彼此幫助，并締結了友誼。

　　17歲的女孩Gretchen（亨特·莎弗 Hunter Schafer 飾）被迫與家人一起搬到一個度假勝地，而那里并不像看上去的那樣平靜。

 奧吉（雅各布·特瑞布雷 Jacob Tremblay 飾）是一個10歲的男孩，除了頭戴一個巨大的太空頭盔外，他和其他的同年齡孩子別無二致。頭盔下隱藏了奧吉因為各種手術而傷痕累累的臉龐，它不僅完美的隱藏起了奧吉脆弱自卑的內心，也成功的防止了奧吉的模樣嚇到別的孩子。奧吉沒有上過學，他的所有文化知識都是母親伊莎貝爾（朱莉婭·羅伯茨 Julia Roberts 飾）在家教授給他的。然而，伊莎貝爾漸漸感覺到，家庭課堂無法滿足奧吉的成長需要，除了學習知識，奧吉還必須學會的，是如何同除了家人以外的人交流。在憂慮重重之中，伊莎貝爾將奧吉送入了一間公立學校里，在那里，奧吉面臨的是他人生中必須要戰勝的挑戰。

　　Can I Get a Witness? tells the story of a mother and daughter in a near-future world where huge sacrifices are made to maintain life on Earth.　　With its resources swallowed by e-waste and overpopulation, the world is experiencing an anthropogenic collapse. To manage, technological advances are shunned. Nobody has electricity and only people with exceptions are permitted cars. Most importantly, there is also a collective agreement that nobody is allowed to live beyond the age of 50.　　Oh’s Ellie lives with her teenage daughter Kiah (Keira Jang), who is starting her first day as a Documenter, an important role in this new world order. She uses her artistic gifts — beautifully conjured in animations — to draw the dying ceremonies, since printing and photography have been banned.　　Kiah is paired with Daniel (Joel Oulette), the young man who performs the contractual elements of each person’s end-of-life ceremony. He matter-of-factly provides the packages a person can choose, sets them up when the time comes, and performs the burials. But his new coworker is having a hard time handling the emotional impacts of the job.