麥可(狄恩肯恩飾)在路上搭載了年輕性感的正妹(克莉絲汀波森飾)，麥可原先認為漫漫公路有正妹相伴艷福不淺，自以為遇上了豔遇的他，卻不知道自己即將陷入一連串的陰謀及殺機，一趟沒有終點的旅程即將展開…　　故事描述一個男人在路途中載了一位年輕的女人，原來只是好心借人搭便車，結果男主人公卻發現自己陷入了一場可怕的午夜夢魘……　　If she looks too good to be true, then she absolutely is. Just ask Michael Anderson (Dean Cain), a gullible film editor who picks up a sexy young hitchhiker (Christie Burson) in the Arizona desert. After the most thrilling one night stand of his life, Michael becomes embroiled in a twisted love con involving a sadistic crime boss (Michael Madsen), a lonely henchman, and a thieving bank manager. Trust isn't just a bitch, it's a dirty little trick!　　A crime bosss money is missing and he wants it back by any ay means. The beautiful hitchhiker has it and wants to make the getaway.　　Alexander "Sasha" Shulgin is the scientist behind more than 200 psychedelic compounds - including MDMA, more commonly known as Ecstasy. Considered to be one of the greatest chemists of the 20th century, Sasha's vast array of discoveries have had a profound impact in the field of psychedelic research, making him a subject of fascination and controversy among fellow scientists and a folk hero to recreational users of psychedelics. Dirty Pictures uncovers the lifework of Dr. Shulgin and takes  viewers inside his Northern California home where he lives with his wife of 40 years and continues to carry out experiments in a makeshift laboratory. Director étienne Sauret likewise delves into the broader world of psychedelic research - where the fields of chemistry, neuroscience and philosophy intersect - and investigates whether or not this particular field could aid in solving the deepest mysteries of the human mind.

　　小說家丹尼爾（奧斯卡·馬丁內茲 Oscar Martínez 飾）從剛出道起事業就順風順水，如今更是獲得了諾貝爾文學獎的殊榮，攀登上了職業的頂峰，然而這榮譽卻并未帶給他滿足，恰恰相反，丹尼爾擔心名聲和財富會奪走他文學創作上的靈感與鋒芒?！　∫换窝畚迥赀^去，丹尼爾熱度不減，邀約和獎項不斷，可冷淡而又避世的他只教助手一一回絕。一封來自小鎮薩拉斯的信吸引了丹尼爾的注意，薩拉斯是他闊別已久的故鄉，如今邀請他踏上故土，接受“杰出公民”的獎項，在未告知媒體和朋友們的情況下，丹尼爾獨自踏上了返鄉的旅途，在那里，他再度見到了曾經的戀人艾琳（安德麗婭·弗里杰里奧 Andrea Frigerio 飾），如今的艾琳早已經嫁為人妻，而她的丈夫正是丹尼爾的舊友安東尼奧（達迪·布列瓦 Dady Brieva 飾）。

　　20世紀70年代，在日本中小學生中間流傳著這樣一個恐怖的傳說：放學獨自走到公園附近時，會遇到一個帶著白色口罩、穿紅色風衣的女人。遇到路過者，她會摘下口罩，露出裂到耳朵的恐怖大嘴，問對方“我漂亮嗎？”如回答不漂亮，她會將對方毀容；若回答漂亮，她就將對方變得和自己一樣；如果逃跑，她會以極快的速度追上。這個女人的名字就叫：裂口女。　　各學校一時間人心惶惶，男女學生們都怕碰到這個可怕的女人，而大人們卻對這個謠言嗤之以鼻。但隨著一場不詳的地震發生，裂口女終于到來……

　　一場與虐殺狂魔的生死競速就此展開——販賣幸存者拼死追蹤被綁少女，而自其失蹤后，每一小時流逝都令少女的生機愈加岌岌可危