ISSAC is an intense psychological thriller which constantly treads the lines of reality and fiction. Issac, A young reclusive mortician who inherited his stepfather's mortuary business meets a friendly waitress, Cassi. The two create an instant connection and after a night of terror, they pursue a revenge murder together. This film mixes a realistic story with surreal imagery, showing how one in isolation may operate due to the circumstances he has been given. Issac inevitably makes a choice and never questions the morality of his decisions.

　　當一位孤獨的真正犯罪迷遇到她最喜歡的播客主持人時，浪漫擦出了火花，但事情很快變得奇怪，因為他對她的迷戀變成了癡迷，而他最新的劇集似乎圍繞著她最終的謀殺展開。

洛杉磯警探喬瑟夫（克萊格·謝菲爾 飾）是個標準敗類，嗑藥嗑得比誰都勤快，調查命案不忘順手牽羊，更枉顧家中妻小，專搞迷人可愛的阻街女郎。一宗幼童謀殺案現場，喬瑟夫撿回一只受過詛咒的奇異盒子，打開后怪事不斷一樁接一樁：昨夜搞上的妓女意外身亡，他瞬間成為頭號嫌疑犯；一連串似幻似真的恐怖體驗更不斷尾隨，無臉怪人四處追殺人群，《養鬼吃人》系列當家猛鬼－針頭鬼（Pinhead）也重出江湖，一個頭兩個大的喬瑟夫該如何解決這謎一般的虛實夢魘？本片改編自克里夫巴克（Clive Barker）恐怖小說「受地獄羈絆之心」The Hellbound Heart，這顆壞心腸的主人正是故事男主角喬瑟夫，身為警察的他自身行為不檢點也罷，涉嫌謀殺難以脫罪的他竟然嫁禍好同事，善惡終有報，惡徒喬瑟夫果然陷入萬劫不復的魔鬼夢魘，活著比死更痛苦。

　　The main character is Dr. Max Holst, a successful neurosurgeon. One day an intense little man named Steinmetz shows up, who has the real ability to create objects out of thin air, using only his mind. As no one believes him at first, he is held at a ward for mental patients, but manifests the key to his door and escapes. As he has a special interest in Dr. Holst, Steinmetz subsequently invites Holst to his large mansion, which is full of expensive paintings and sculptures, and proves to him that he can in fact materialise objects. Steinmetz’s abilities are evolving by leaps and bounds, and is progressing from being able to create objects only to being able to create living things. His ultimate ambition is to be able to create a human being. He tells Dr. Holst that if he will only perform a certain brain operation on him, Steinmetz will become able to attain his goal. He’s got all the necessary equipment set up in his basement. Dr. Holst, however, is too spooked by the whole thing to agree to this mad scheme, and refuses. Steinmetz then sets about manipulating Holst’s life, to pressure him into performing the operation. By then Steinmetz has become able to create a temporary human being, and in the hope that he can perhaps make his own creation perform the operation, he manifests a doppelganger of Dr. Holst. This double proceeds to take over Dr. Holst’s life, creating chaos for him professionally and personally. And then Dr. Holst starts fighting back. The ending has the dual virtue of being both unexpected and satisfying.