一名醫生因一連串令人震驚的兇惡案而入監服刑，他忠心的妻子打算模仿同樣的殺人手法作案，借以證明他的清白。

　　The nightmare was about a demonic possession. A long time ago, there was an evil in a small town and it was jealous of the girl and would never let her go, since the devil loved the girl. One night, the evil raped the girl and she became pregnant. After months the girl could not hide her baby, her father figured her secret out and clapped the girl in irons and locked her room door. But the evil put the gun to her father' temple and saved the girl. The father had a stroke and had been sleeping on the bed for three months and died. Time went on and the girl brought a child into the world. Naturally, people who were living in the village heard the story and they did not want to see neither the girl nor the baby since when the baby was born, plants dried in the field, fishes lost in the lake and people had prayed to the god for rain, but nothing changed in the village. People got so angry, dug a hole in front of the fountain, put her into the hole and threw stones at her face. The girl died soon after. The evil went off the deep end, took a revenge of the village and killed everyone except two sisters because the evil wanted them to take care of its baby...

　　哈瑞（杰瑞德·萊托 Jared Leto 飾）和瑪麗安（詹妮弗·康納利 Jennifer Connelly 飾）彼此相愛，夢想著開個服裝店，夢想著有個美好的明天。然而他們都離不開毒品，并想著以銷毒賺得第一桶金。哈瑞的母親是個徹底的電視迷，最大的夢想是上電視，為此不顧年邁吞食減肥藥。由于藥品里的毒品成分，她漸漸上了癮。哈瑞的朋友狄龍（馬龍·韋恩斯 Marlon Wayans 飾）同樣是個癮君子，為了掙大錢加入了黑社會。為了夢想，他們努力著，卻一步步深陷毒品難以自拔。 哈瑞的胳膊因注射毒品感染而被割去；瑪麗安為了毒品出賣肉體和自尊；哈瑞的母親最終住進了精神病院受盡折磨；狄龍鋃鐺入獄。當視線變得模糊，夢在遙遠處呼喚，迷失的人該以怎樣的姿態安撫自己的靈魂。

　　阿里曾是一位年輕的教師，他辭去了工作，卻被父親無情地趕出了家門。在感到迷茫和孤獨之際，他重新找到了舊友，這一舉動觸發了他一段深刻的自我探索之旅。