兩個不善社交的少女，一天晚上無聊，轉向互聯網尋找恐怖故事。他們在一個令人毛骨悚然的網絡上找到了一個游戲，聲稱你可以用你的手機來召喚超自然...如果你輸了比賽...你失去了生命

　　一位是作風矯健、機智幽默的聯邦特工威斯特（威爾·史密斯 Will Smith 飾），一位是愛耍聰明的易容大師高登（凱文·克萊恩 Kevin Kline 飾），這兩個看似一山不容二虎的狠角色卻被總統同時召見了，原因是授命他們一同追捕一名神秘毒辣的科學家連環殺手。威斯特和高登只好在摩擦碰撞中培養默契，竟然很快成為一對絕配拍檔。經過調查，兩人發現原來幕后黑手竟然是曾經的天才博士勒弗里斯（肯尼思·布拉納 Kenneth Branagh 飾），他因在一次實驗中失去雙腿，只好永久呆在輪椅上，然而殘缺的個性與對社會的怨恨讓他開始到處作亂，甚至發明了一架巨型的蜘蛛機器濫殺無辜，并企圖謀殺總統，統治美國。危機迫在眉睫，威斯特和高登分頭來到新奧爾良，駕駛著一列布滿機關的火車迎戰蜘蛛博士，一場古怪武器間的斗智斗勇已悄然展開……

　　The boisterous, arrogant professor Challenger, a reputed biologist and anthropologist, dares the London Zoological Society to mount an expedition to verify his spectacular claim, without physical proof, that his previous expedition to the Amazonian basin found live dinosaurs. Apart from him and his 'socialite' counterpart, professor Summerlee, it consists of experienced discoverer Lord Roxbury, the young reporter Ed Malone -who got publicly struck down with Challenger's umbrella at his arrival- and Jennifer Holmes, Malone's news agency's boss's daughter, essentially as conditions for putting up the money. In Brazil they are joined by Jennifer's brother David and local 'guide' Manuel Gomez. They soon discover the dinosaurs are real and dangerous, like giant spiders, but loose their helicopter and thus are desperate for a way down from the isolated plateau. They learn Roxbury knew about the fate of Burton White, an explorer whose diary they find, thus presume to be dead, in search of diamonds, and confirmation of the local tribe being the lethal guardians of the plateau's secrets, but also get surprising help...

27歲的由嘉里沉迷于擬人化燒肉漫畫《肉即吾命》，卻始終無法接納真實的自己。面對朋友們紛紛步入婚姻與家庭，她感到焦慮與孤獨，嘗試通過相親改變現狀，卻屢遭不順，醉倒在歌舞伎町街頭。此時，她被陪酒女萊伊救起，兩人由此展開一段微妙的關系。隨后，由嘉里又結識了已婚男公關朝日，三人各自背負著不同的生活壓力，卻在彼此陪伴中逐漸找到歸屬與勇氣。                                                                      　　影片改編自金原瞳撰寫的同名小說。